All data is based on the New World Preview Client and will change before release!
The Great Axe is a two-handed weapon focused on Damage. The "Reaper" tree has a lot of single-target damage, movement speed and self-healing, while the "Mauler" tree grants access to AoE abilities such as Whirlwind and some Crowd Control that allows players to pull targets to them. The Greax Axe also has limited taunt capabilities.
Great Axes benefit solely from Strength.